Dietary fat overload reprograms brown fat mitochondria

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Dietary fat overload reprograms brown fat mitochondria

Chronic nutrient overload accelerates the onset of several aging-related diseases reducing life expectancy. Although the mechanisms by which overnutrition affects metabolic processes in many tissues are known, its role on BAT physiology is still unclear. Herein, we investigated the mitochondrial responses in BAT of female mice exposed to high fat diet (HFD) at different steps of life. Although ...

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ژورنال

عنوان ژورنال: Frontiers in Physiology

سال: 2015

ISSN: 1664-042X

DOI: 10.3389/fphys.2015.00272